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Course Content

14 - Measurement of Uncertainty

Overview

Purpose

Every result has some degree of uncertainty that comes from the calibration of the method and the analysis itself. In this activity, participants learn how to determine measurement uncertainty using a top-down approach and how to apply measurement uncertainty in an advisory capacity for their clients.

Key Message

  • The uncertainty gives the limits of the range in which the true value of the measurand is estimated to be at a given probability.
  • The long-term %CV or SD data gained through the laboratory’s IQC is sufficient for satisfying the minimal criteria for MU determination.
  • The MU is helpful in differentiating whether a change in a serial test result is due to analytical variation or a true physiological change.

Self Assessment

Can you: 

  • Recognize the need for hospital management support and analytical staff adherence when planning a QC program?
  • Identify the steps needed during the planning phase to successfully implement a QC program?
  • Further refine the process plan to identify what happens, who’s responsible, and by when?


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